When we bought our first licenses, it was not yet natively available for Linux and hence we did run it under WINE, where it performed very well. We have also put in one feature request: Virtual agarose gel images for partial restriction enzyme digests. It is under active development: new features are added constantly.It has a free version, the SnapGene Viewer, that everybody can download and use to view and print plasmid maps.It is not as expensive as the GeneConstructionKit or Clone Manager.SnapGene reads among others: ApE, Clone Manager, DNASTAR Lasergene®, DNA Strider, EMBL (ENA), EnzymeX, GenBank/DDBJ, Gene Construction Kit®, MacVector, pDRAW32, Serial Cloner and Vector NTI®. This was important for us as we had hundreds of our plasmid maps made with GeneConstructionKit. It is able to open almost all other sequence formats.True cross-platform: it runs on both Windows and Mac, and now even natively on Linux!.Just around that time, SnapGene was released and it fulfilled almost all of our requirements: I suppose that the codebase of GCK is probably more than 20 years old and for that reason nobody dares to touch it. We contacted the developers of GCK, but they apparently were either not willing or able to help us. However, with the upgrade to version 4, GCK became unusably slow under WINE and we were looking for a replacement. However, since several of our computers run Ubuntu Linux, we did run GCK versions 2.5 and 3 using WINE (a compatibility layer that allows us to run native Windows programs under Linux). The latter runs unfortunately only under Windows.

Among those that we liked a lot for a long time were Textco's GeneConstructionKit (GCK) and Clone Manager (Professional). Our lab has been using different software packages to plan, document and visualize DNA constructs.

Crack geneious trial